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劇情：該片根據公安部督辦的四川516特大制販毒品案的真實改編而成。在大川市的一條國道上，緝毒大隊大隊長曹仁凡與一名劫持公交車的在逃毒販展開激戰。他從槍林彈雨中救出了人質，并抓獲了毒販彭家豪。緝毒小組深入調查分析，摧毀了幕后毒梟精心策劃的尋找警察臥底的陰謀，并以彭家豪為誘餌，將東南亞毒品原料大亨“巧哥”抓捕歸案。植根于六甲山的毒窩已經暴露，禁毒專案組與近百名特警和令人發指的販毒集團展開了一場殊死搏斗，發誓要摧毀這個龐大的犯罪團伙。展開 
